5 Results for "

Polyscias guilfoylei (Cogn. & Marchal) Bailey

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Polyscias guilfoylei (Cogn. & Marchal) Bailey" in MCE Product Catalog:

1
Emodinanthrone
Emodinanthrone
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1 Cited Publications
Cat. No.: HY-N9362
CAS No.: 491-60-1
Synonyms: EmodAN
Category:  

Infection Phenols Polyphenols Plants Rhamnaceae Aconitum nagarum var. acaule (Finet & Gagnep.) Q. E. Yang Disease Research Fields

Target:  

Ferroptosis Antibiotic

Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC50=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .
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Ladyginoside A
Ladyginoside A
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Cat. No.: HY-N16656
CAS No.: 38424-95-2
Category:  

Triterpenes Terpenoids Polyscias fruticosa (L.) Harms Plants Araliaceae

Target:  

Amylases Glycosidase

Ladyginoside A is a triterpenoid saponin found in the leaves of Polyscias fruticosa (L.) Harms. Ladyginoside A has inhibitory activities against α-amylase and α-glucosidase, and can regulate carbohydrate metabolism. Ladyginoside A also exhibits potential anti-inflammatory and mast cell stabilizing effects. Ladyginoside A can be used for the researches of inflammation and metabolic disease, such as diabetes .
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COOH-C3-CONH-C7-COOH
COOH-C3-CONH-C7-COOH
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Cat. No.: HY-163758
Target:  

PROTAC Linkers

Research Areas:  

Cancer

COOH-C3-COGN-C7-COOH is a PEG based linker for PROTAC. COOH-C3-COGN-C7-COOH can be used for synthesis of PROTAC Degrader ARM165 (HY-163677) .
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Emodinanthrone (Standard)
Emodinanthrone (Standard)
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Cat. No.: HY-N9362R
CAS No.: 491-60-1
Synonyms: EmodAN (Standard)
Category:  

Phenols Polyphenols Plants Rhamnaceae Aconitum nagarum var. acaule (Finet & Gagnep.) Q. E. Yang

Target:  

Reference Standards Antibiotic Ferroptosis

Pro-xylane (Standard) is the analytical standard of Pro-xylane. This product is intended for research and analytical applications. Emodinanthrone (EmodAn) is a MARCH7 stabilizer that inhibits ferroptosis (EC50=70 nM). Emodinanthrone is also a precursor to Emodin (HY-14393) and possesses antibiotic activity. Emodinanthrone directly binds to MARCH7 and blocks its ubiquitination-mediated degradation at the K608 site; this action enhances MARCH7-mediated K48 ubiquitination and degradation of NCOA4, as well as its regulation of the intracellular localization of TFR1 via K63 ubiquitination, thereby reducing the intracellular labile iron pool and blocking ferroptosis. Emodinanthrone demonstrates in vivo cardioprotective effects and exhibits a favorable safety profile. Emodinanthrone is applicable to research on ferroptosis-related cardiovascular diseases, including Doxorubicin (HY-15142A)-induced cardiomyopathy and myocardial ischemia-reperfusion injury .
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Pelargonium hortorum extract
Pelargonium hortorum extract
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Cat. No.: HY-N20067
Synonyms: Pelargonium; Pelargonium x hortorum extract
Category:  

Extract

Target:  

Others

Pelargonium hortorum extract (Pelargonium) is an extract of geranium (Pelargonium hortorum LH Bailey) containing a variety of bioactive components.
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